CD4 and COVID-19: To determine whether and how CD4+ helper T cell activation by SARS-CoV-2 peptides is affected by the presence of helminth antigens, we examined the frequency of activated CD4+ T cells expressing simultaneously CD69 and CD137 in PBMCs of convalescent COVID-19 patients following stimulation with SARS-CoV-2 peptides alone (SPP), or in combination with helminth antigens (OvAg, BmAg or AlAg).