Gene Ontology (GO) biological processes enrichment analysis of the significantly differentially expressed genes (DEGs) in Alkbh5-deficient neutrophils compared with WT neutrophils showed that neutrophil migration made up the most significantly enriched biological processes with annotations of neutrophil association upon deletion of ALKBH5 at both the early and late stages of sepsis (Fig. 4c, d). This evidence concerns the gene ALKBH5 and Sepsis.