ALKBH5 and Autoimmunity: We previously reported that m6A RNA demethylase ALKBH5 can rewire α-ketoglutarate dehydrogenase (OGDH)-itaconate metabolism to promote viral replication in macrophages.15 Recent study revealed a specific function of ALKBH5 in controlling CD4+ T cell-mediated pathogenesis in autoimmunity.16 However, the intrinsic role of m6A RNA modification and ALKBH5 in neutrophils in antibacterial immunity is still unknown.