MUC5AC and neoplasm: Based on anincreased B-lymphocyte infiltration of cancers in the MUC5AC knockdown mice, theseauthors suggested that MUC5AC neo-expression on the surface of pancreatic cancercells may aid cancer cells to escape from anti-tumor effects of the immune system.37 This concept is also supported by data published by Hoshi et al., providingfunctional evidence for MUC5AC suppressing antitumor effects of neutrophils.32