Based on anincreased B-lymphocyte infiltration of cancers in the MUC5AC knockdown mice, theseauthors suggested that MUC5AC neo-expression on the surface of pancreatic cancercells may aid cancer cells to escape from anti-tumor effects of the immune system.37 This concept is also supported by data published by Hoshi et al., providingfunctional evidence for MUC5AC suppressing antitumor effects of neutrophils.32 The gene discussed is MUC5AC; the disease is cancer.