CASP3 and neoplasm: Additionally, histological analyses revealed that LP treatment increased the proportions of CD11c+ dendritic cells (DCs) by 3.7-fold, iNOS+ M1-like macrophages by 7.3-fold, CD8+ T cells by 5.2-fold, Casp3+ apoptotic cells by 2.3-fold, and PD-L1+ tumor cells by 6.1-fold within tumors compared with those in the control group (figure 2B).