This demonstrated no associations with offspring atopic eczema, although there are indications of higher ORs for atopic eczema with rs10741657 (CYP2R1) at ages 12 and 24 months: OR 1·42 (95% CI 0·95–2·12, P = 0·09) and OR 1·37 (95% CI 0·95–1·96, P = 0·09), respectively (Table 4). The gene discussed is CYP2R1; the disease is atopic eczema.