FPR1 and chronic obstructive pulmonary disease: Full-length IL-36γ was converted to the active form by both nonsmoker and COPD N-Formylmethionine-leucyl-phenylalanine–activated (fMLP-activated) neutrophils, although data suggest that basally released COPD neutrophil products may be able to cleave IL-36γ (Figure 8, B and C).