KCNH2 and torsades de pointes: Block of hERG (human ether-à-go-go-related gene) currents by several non-cardiovascular drugs has the potential to induce QT interval prolongations in the electrocardiogram (ECG) and life-threatening Torsades de Pointes (TdP) cardiac arrhythmias (review in Keating and Sanguinetti (1996); for a compilation of torsadogenic drugs see www.crediblemeds.org).