For example, tubular TENM2 expression correlated positively with eGFR (p=1.6×10−8; Fig. 2e) and negatively with tubulointerstitial fibrosis (p=2.0×10−9; Fig. 2f), tubular DCLK1 expression correlated positively with fibrosis (p=7.4×10−16; Fig. 7c), and tubular SNX30 expression correlated positively with eGFR (p=5.8×10−14) and negatively with fibrosis (p<2.0×10−16). Here, TENM2 is linked to fibrosis.