HSP70 can also exert different effects on CHIP‐dependent ubiquitylation of TP63 isoforms (a homolog of the p53 tumor suppressor), that is, it potentiates ubiquitylation of the TAp63 isoform and reduces modification of the ΔNp63 isoform (Wu et al, 2021). This evidence concerns the gene STUB1 and neoplasm.