Moreover, intertumoral injections of c‐Met CAR mRNA electroporated T cells into patients with metastatic breast cancer brought about wide tumour necrotic zones mainly achieved by cytolytic function mediated by mRNA c‐Met‐CAR T cells at the injection site; a lack of c‐Met immunoreactivity, and the recruitment of macrophages into intratumor areas, causing an inflammatory response within tumours. The gene discussed is MET; the disease is breast cancer.