CRP and neoplasm: Notably, in a subgroup analysis of those patients with laboratory parameters available prior to surgery, the inclusion of preoperative haemoglobin (HR: 0.809; 95%CI: 0.684–0.57; p = 0.014) and CRP‐levels (0.998; 95%CI: 0.684–0.957; p = 0.625) – both significantly associated with altered OS in the univariate analysis – further diminished the effect of lrRBCT on OS (HR: 1.677; 95% CI: 0.806–3.492; p = 0.167), irrespective of age (p = 0.011), amputation status (p = 0.023), grading, tumour size, depth, or histological subtype (all p > 0.05).