LIPC and Decreased liver function: To our knowledge, the effect of histologically confirmed hepatopathy alone on serum DGGRlipase activity (presumptively through release of hepatic lipases) has not been reported.Anecdotally, we have observed mild elevations in serum lipase activity in dogs with elevatedliver enzyme activity (alanine aminotransferase [ALT], alkaline phosphatase [ALP]) but withouta clinical suspicion of pancreatitis, which could reflect release of hepatic lipases in dogswith hepatopathy.