The results show that ZNF273, ZBTB37, TRIM52, TSGA10, ZNF727, TRAF2, TSPAN17, USP28, and ZNF519 were identified in at least two interaction networks, in which ZNF273, ZBTB37, and ZNF727 are related to 5-year or 10-year survival in breast cancer. The gene discussed is ZNF727; the disease is breast cancer.