CHI3L1 and neoplasm: With the deepening of tumor infiltration, especially the infiltration depth of more than 2/3 of the full thickness, the positive rate of CHI3L1 (85.7%, 18/21) was significantly higher than that of the infiltration depth of less than 1/2 of the full thickness (50%, 21/42) and the positive rate of more than 1/2 but less than 2/3 full-thickness (82.5%, 33/40).