METTL3 and acute myeloid leukemia: In addition, further investigation is also required on whether METTL3-mediated MYC mRNA m6A methylation modification affects the half-life and stability of MYC mRNA, and whether some para-signaling pathways participate in the inhibitory role of MEG3 in the chemoresistance of AML through the miR-493-5p/METTL3/MYC axis.