EGF and neoplasm: The tumor-promoting activity of EntF* was further confirmed by macroscopically assessing the number of nodules on the cecum of treated mice: EntF*-treated samples showed a 3-fold increase in the number of nodules compared to PBS vehicle (p = 0.036) (Fig. 3e, f), whereas EGF-treated samples showed a 4.5-fold increase compared to control (Fig. 4b).