PIK3R3 and endometrioid adenocarcinoma: Cystadenocarcinoma, serous, and endometrioid carcinoma tissues were stained “medium” or “weak” for PIK3R3, whereas no detectable intensity was observed for normal tissues (described as “not detected”), suggesting that PIK3R3 expression is specifically upregulated in ovarian carcinomas (Fig. 1E).