Therefore, the expression of KLF4 and the autophagy markers LC3-B/LC3-A and Beclin-1 was abnormally decreased in the endometria of adenomyosis patients, and there was a moderate positive correlation between KLF4 and autophagy markers (LC3-B/LC3-A and Beclin-1). The gene discussed is BECN1; the disease is adenomyosis.