TNFSF11 and plasma cell myeloma: We also observed lower levels of Tnfsf11 and Sost mRNAs, as well as lower levels of RANKL and sclerostin proteins, in Ciita-knockout osteocytes compared to wild-type osteocytes from mice bearing myeloma, while there was no difference in the expression of those cytokines in osteocytes from mice without myeloma (Fig. 2o, p).