Because exogenic LL-37 loses its activity in CFsputum, treatment of patients with it may be detrimental, which canbe reflected in other endogenous AMPs in natural surroundings.40,48 Combining all of the properties, our study suggests that syntheticpeptides may be useful for treating CF-associated lung infectionsin contrast to LL-37. Here, ADSL is linked to cystic fibrosis.