Isolate 895 was inoculatedto 895 CF diluted sputum to eliminate the possibility of a certainelement in the CF sputum that gives a specific isolate an advantage.LL-37 lost its activity in the presence of the mixed CF sputum withkilling rates of 13.23%, 11.73%, 34.24%, and 11.48% toward isolates24, 46, and 82 and PAO1, respectively. The gene discussed is SMOX; the disease is cystic fibrosis.