ADSL and cystic fibrosis: However, the biofilm inhibition activity of Amp1D was foundto fade at sub-inhibitory concentration, while Seg6D and Seg5D preservedtheir activity in the CF clinical P. aeruginosa isolates,indicating the importance of the ability of the AMPs to adhere tothe bacteria to prevent biofilm formation at sub-inhibitory concentrations.When this is taken into consideration, the activities of these peptidesare the same, once the peptides are penetrating the cell wall.