AD that is linked with presenilin mutation is also characterized by increased levels of monocyte chemoattractant protein 1 (MCP‐1), IL‐6, and IL‐8 while a Presenilin1 mutation in microglial cells amplified tumor necrosis factor α, IL‐1α, IL‐1β, and IL‐6 gene expression.72 This evidence concerns the gene IL6 and Alzheimer disease.