HP and gastritis: After the acute gastritis infection of mice was treated with Lla-Met, the amount of Hp colonization was significantly reduced compared with that of those treated with the standard triplet of omeprazole, amoxicillin and metronidazole; through HE staining of the gastric mucosa tissues of mice, showed less inflammatory cell infiltration compared to standard triplet and OPZ+Met+Lla, suggesting that Lla-Met could significantly improve the inflammatory response of acute gastritis in the stomachs of mice.