NLRP3 and Alzheimer disease: Actually, according to previous studies, pathological processes such as Alzheimer’s disease result in fragmentation of the Golgi apparatus, and infection with HCV and human rhinovirus (HRV), or intracellular bacteria such as Shigella, can also perturb Golgi architecture dispersal to varying degrees (51, –, 53), and all of these cause NLRP3 inflammasome activation (18, 54, –, 56).