We also verified that miR-380-3p suppressed E-cadherin but increased the expression levels of N-cadherin and Vimentin to facilitate epithelial–mesenchymal transition (EMT) process in the PC cells (Figure 2(e-g)), and Transwell assay results confirmed that miR-380-3p acted as an oncogene to facilitate cell migration in the PC cells (Figure S4C, D). Here, CDH2 is linked to pachyonychia congenita.