Because allergy is primarily mediated by a type 2 adaptive immune response, we then tested Hp‐TGM in a T cell‐dependent model of airway sensitization and challenge, using HDM extract [60], with intraperitoneal administration of Hp‐TGM during allergen sensitization (day 0) or at each day of challenge (day 7–11) (Figure 3a). The gene discussed is HP; the disease is allergic disease.