NLRP3 and COVID-19: Additionally, plasma levels of LBP have been found heightened throughout the hospital stay in COVID-19 patients with elevated markers of cardiac involvement (N-terminal pro-B-type natriuretic peptide, troponin T, troponin I) and positively correlated to levels of inflammasome activity markers, which are associated with cardiac involvement too, suggesting that gut leakage with subsequent LPS-driven priming of the NLRP3 inflammasome may have a role in the pathogenesis of cardiac involvement during COVID-19 (234).