In a study using the same model, Kim et al. found that TSLP receptor-deficient (Tslpr−/−) mice showed a markedly reduced response of ILC2s and improvement in MC903-induced skin inflammation, whereas disruption of IL-33 (Il33−/−) or IL-25R (Il17rb−/−) did not affect the ILC2 responses (5). Here, CRLF2 is linked to dermatitis.