Bereta et al. observed increased bacterial aggregation at tumor sites by expressing a specific single-chain antibody fragment for carcinoembryonic antigen (CEA) on S. typhimurium VNP20009 (59); Massa et al. increased bacteria’s invasiveness against CD20+ lymphoma, while reducing non-specific aggregation by binding anti-CD20 antibody to the surface of Salmonella (60). The gene discussed is CEACAM5; the disease is neoplasm.