We conducted univariate Cox regression analysis to investigate the prognostic value of m5C regulatory genes and screened NSUN2 (HR=5.428, 95%CI=1.645-17.905, P=0.005), TET3 (HR=2.956, 95%CI=1.017-8.593, P=0.047), and YBX1 (HR=3.428, 95%CI=1.403-8.347, P=0.007) that were associated with the prognosis of PCa (Figure 2A; Supplementary Table 2). This evidence concerns the gene YBX1 and posterior cortical atrophy.