However, within the reference range and after exclusion of users of potentially immunomodulating medication, both IgA (HR: 1.34; 95% CI: 1.06-1.70) and IgG (HR: 1.13; 95% CI: 1.01-1.26) were associated with an increased risk of definite incident pneumonia after six years of follow-up (Supplementary Table S4). This evidence concerns the gene CD79A and pneumonia.