Krüppel-like factor 7 (KLF7) is a member of the KLF family of zinc finger transcription factors and has antioncogenic functions in multiple cancer, such as human oral squamous cell carcinoma (OSCC) (43), glioma (44), gastric cancer (45), endometrial cancer (46), ovarian cancer (47), and non−small cell lung cancer (48). Here, KLF7 is linked to oral cavity squamous cell carcinoma.