REN and nephrosclerosis: Electrolyte differences (primarily calcium, phosphorus, and potassium) leading to imbalances in recipientErythropoietin and renin structure dissimilarity between porcine donors and recipients causing anemia and hypoaldosteronismProtein wasting in renal xenografts contributing to hypoalbuminemia and graft lossHypertensive nephrosclerosis due to higher blood pressures in recipient than in porcine donor