CD8A and inherited rippling muscle disease: When dissecting the relative abundance of the different subpopulations, we observed that the abundance of CD8+ CD27+ GZMB/K+ cells, but not CD8+ memory GZMB/K+, was lower in RMD patients compared to non-RMD individuals, and comparable in b-DMARD- and cs-DMARD-treated patients (Figure 5E).