Similarly, serum CRP and insulin were associated with intermediate hyperglycemia (OR 3.35 [95%CI: 1.13,9.93]; p = 0.02, OR 5.93 [95%CI:1.82,19.34]; p = 0.003, respectively) and obesity (OR 14.75 [95%CI:7.35,29.60]; p = 0.001, OR 5.824 [95%CI: 3.24,10.45]; p = 0.001, respectively), and serum adiponectin was only associated with obesity (OR 0.43 [95%CI: 0.26,0.71]; p = 0.001) and was not associated with intermediate hyperglycemia (OR 0.76 [95%CI: 0.31,1.89]; p = 0.5). This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.