VEGFA and neoplasm: From disrupting BBB by targeting junctional proteins, zonula occludens-1 (ZO-1), occludin and β-catenin, to angiogenic, infiltration and migration of glioma cells by downregulating MMP2, MMP9, VEGF, all these tumor promoting processes are modulated by several miRNAs (Petrescu et al., 2019).