AGT and cardiac hypertrophy: ARS or DHA alleviates atherosclerotic lesions in high-fat diet-fed ApoE−/− mice [36, 37], protects against cardiac hypertrophy in vivo, blocks angiotensin II-induced cardiac hypertrophy in vitro in a concentration-dependent manner [38], and attenuates hepatic steatosis and inflammation in diet-induced obese mice [39, 40].