Recently, there have been several studies investigating the association between genetic polymorphisms in TGFBR2 in various diseases, such as abdominal aortic aneurysm, papillary thyroid carcinoma, and end-stage renal disease, especially two promoter polymorphisms rs764522 (-1444C/G) and rs3087465 (-834A/G) [23–25]. Here, TGFBR2 is linked to stage 5 chronic kidney disease.