GPHB5 and metabolic syndrome: The results showed that serum GPHB5 levels did not change significantly during the OGTT in both normal controls and MetS individuals (from 3.43 ± 1.15 to 3.55 ± 1.35 μg/L at 30 min, and then to 3.51 ± 1.18 μg/L at 60 min, and finally to 3.48 ± 1.32 μg/L at 120 min), while AUCGPHB5 in MetS patients was significantly higher than that of controls (Figure 4A).