INS and metabolic dysfunction-associated steatotic liver disease: Furthermore, only a few natural products and food items have been translated into clinical trials, for example, resveratrol, orange, grape, walnut, soy, and mushroom improve insulin secretion and sensitivity, modulating several risk factors such as obesity, dyslipidemia, lipid peroxidation, coronary artery abnormalities, and Non-Alcoholic Fatty Liver Disease (NAFD) (14, 15).