CD4 and breast neoplasm: Total numbers of IFN-γ-producing Th1 and IL-17-producing Th17 cells were significantly increased in the breast tumors of 4T1+d-MAPPS-treated animals (Figures 5(a)–5(c); p < 0.001) while there was no significant difference in total number of CD4+IL-4+ Th2 cells between the tumors of 4T1+saline- and 4T1+d-MAPPS-treated mice (Figure 5(d)), confirming that d-MAPPS favored generation of antitumorigenic Th1 and Th17 immune response.