In addition, the presence of cDC1 within human melanoma tumors correlated with improved response to anti-PD-1 therapy (Barry et al., 2018) as well as with higher CD8+ T cell infiltration into tumors (Binnewies et al., 2019) which is associated with a positive prognosis across multiple tumor types (Fridman et al., 2012). Here, MPPE1 is linked to neoplasm.