PLA2G7 and familial isolated congenital asplenia: Patients with severe ICAS had relatively higher Lp-PLA2 levels than those with moderate or mild ICAS, but there was no statistically significant difference (150.9 ± 100.0 vs. 110.7 ± 70.7 vs. 108.2 ± 61.7 μg/L, p = 0.152, Figure 3B).