We found that SASH3 expression was increased in breast invasive carcinoma (BRCA), cholangiocarcinoma (CHOL), head and neck squamous cell carcinoma (HNSC), kidney renal clear cell carcinoma (KIRC), and kidney renal papillary cell carcinoma (KIRP) tissues compared with adjacent normal tissues. This evidence concerns the gene SASH3 and head and neck squamous cell carcinoma.