Moreover, by combining SII with PD-L1 expression on tumor-infiltrating lymphocytes three distinctive prognostic groups were identified: the best prognosis was seen in patients with high expression of PD-L1 on TILs and a low SII, while the worst prognosis was seen in patients with a low expression of PDL1 and a high SII. The gene discussed is CD274; the disease is neoplasm.