On the other hand, the M2 subtype is activated by IL-4, IL-10, and IL-13, and expresses anti-inflammatory molecules, such as IL-10, tumor growth factor (TGF-β), CCL17, CCL18, CCL22, mannose receptor C type 1 (CD206), class A scavenger receptor (CD204) and hemoglobin scavenger receptor (CD163), have a low antigen-presenting capacity, and may promote tumor growth and survival by inducing angiogenesis and immunosuppression (96–99). The gene discussed is CD163; the disease is neoplasm.