GSDMA and acute myeloid leukemia: Interestingly, our results also detected a higher expression of PRGs in AML patients including NLRP/CASP/GSDM families, and these PRGs were also significantly enriched in NOD-like signaling pathway and immunoactivated-related pathways, implying that pyroptosis might participate in the progression of AML and was associated with the prognosis of AML.