Univariate analysis showed that eleven clinical and radiological characteristics including age, cirrhosis, enhancement pattern, non-smooth tumor margin, APHE, T stage, microvascular invasion (MVI), satellite nodules, serosal invasion, gamma-glutamyl transpeptidase level, and albumin level were significantly different between the ER and non-ER groups in the training set (all p < 0.05). The gene discussed is GGTLC1; the disease is Cirrhosis.