STK25 and hepatocellular carcinoma: In conclusion, we proved that exosomal miR-4800-3p aggravated the progression of HCC by regulating the Hippo signaling pathway by targeting STK25 in both in vitro and in vivo experiments (Figure 8F), which provided evidence that exosomal miR-4800-3p could be used not only as a potential diagnostic marker for HCC but also as a therapeutic target for HCC.