Apart from HNSC, TP73 was also found to be remarkably higher in numerous pan-cancers, for example, adrenocortical carcinoma (ACC), breast invasive carcinoma (BRCA), esophageal carcinoma (ESCA), brain lower grade glioma (LGG), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), ovarian serous cystadenocarcinoma (OV), prostate adenocarcinoma (PRAD), rectum adenocarcinoma (READ), stomach adenocarcinoma (STAD), thyroid carcinoma (THCA), thymoma (THYM), and uterine corpus endometrial carcinoma (UCEC). The gene discussed is TP73; the disease is rectum adenocarcinoma.