TP53 and familial pancreatic carcinoma: GSEA results reveal that the high-risk group was associated with several cancer progression and metastasis-related pathways, including “cell cycle,” “pancreatic cancer,” “ECM receptor interaction,” “p53 signaling pathway,” “G2M checkpoint,” and “epithelial mesenchymal transition (EMT).” We also investigate the tumor microenvironment difference between two groups.